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91探花
CMP
Credit: Jack Hobhouse

Professor Achillefs Kapanidis

Professor of Biological Physics

Research theme

  • Biological physics

Sub department

  • Condensed Matter Physics

Research groups

  • Gene machines
Achillefs.Kapanidis@physics.ox.ac.uk
Telephone: 01865 (2)72226
Biochemistry Building
  • About
  • Publications

The FRET-based structural dynamics challenge -- community contributions to consistent and open science practices

(2020)

Authors:

Eitan Lerner, Benjamin Ambrose, Anders Barth, Victoria Birkedal, Scott C Blanchard, Richard Borner, Thorben Cordes, Timothy D Craggs, Taekjip Ha, Gilad Haran, Thorsten Hugel, Antonino Ingargiola, Achillefs Kapanidis, Don C Lamb, Ted Laurence, Nam ki Lee, Edward A Lemke, Emmanuel Margeat, Jens Michaelis, Xavier Michalet, Daniel Nettels, Thomas-Otavio Peulen, Benjamin Schuler, Claus AM Seidel, Hamid So-leimaninejad, Shimon Weiss

Single-molecule Analysis Reveals the Mechanism for DNA Opening in Transcription Initiation

Biophysical Journal Elsevier 118:3 (2020) 29a

Authors:

Abhishek Mazumder, Richard H Ebright, Achillefs N Kapanidis

Unravelling the reaction mechanism and kinetics of dnazymes based on bulk and single molecule studies

MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (2020) 1109-1110

Authors:

AM Pag猫s, P de Keyser, V Top, R Andrews, M Hertog, AN Kapanidis, D Spasic, J Lammertyn

Abstract:

In this work we present a mathematical approach to model the kinetic behavior of DNA enzymes (DNAzymes) in order to predict their activity, which will assist future sequence designs. The model has been designed based on multiple previous reports since no general reaction mechanism has been fully described for DNAzymes to date. To better understand this, we also present first of its kind study of the DNAzyme catalytic reaction at the single molecule (SM) level.

Rapid functionalisation and detection of viruses via a novel Ca2+-mediated virus-DNA interaction

Scientific Reports Nature Research 9 (2019) 16219

Authors:

Nicole Robb, Jonathan Taylor, Amy Kent, A Kapanidis, O Pambos, B Gilboa

Confinement-free wide-field ratiometric tracking of single fluorescent molecules

Biophysical Journal Elsevier 117:11 (2019) 2141-2153

Authors:

Barak Gilboa, B Jing, TJ Cui, M Sow, A Plochowietz, A Mazumder, AN Kapanidis

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