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Abstract:

Complex tissue flows in epithelia are driven by intra- and inter-cellular processes that generate, maintain, and coordinate mechanical forces. There has been growing evidence that cell shape anisotropy, manifested as nematic order, plays an important role in this process. Here we extend an active nematic vertex model by replacing substrate friction with internal viscous dissipation, dominant in epithelia not 91̽��ed by a substrate or the extracellular matrix, which are found in many early-stage embryos. When coupled to cell shape anisotropy, the internal viscous dissipation allows for long-range velocity correlations and thus enables the spontaneous emergence of flows with a large degree of spatiotemporal organisation. We demonstrate sustained flow in epithelial sheets confined to a channel, providing a link between the cell-level vertex model of tissue dynamics and continuum active nematics, whose behaviour in a channel is theoretically understood and experimentally realisable. Our findings also show a simple mechanism that could account for collective cell migration correlated over distances large compared to the cell size, as observed during morphogenesis.

Abstract:

An idealised mesoscale model of the enzymatic digestion of starch modelled as a polymer aggregate is used to study the effect of various enzyme properties, such as the enzyme efficiency, range and radius, on the rate at which monomers are released from the aggregate. Depending on the enzyme efficiency the process is found to be either reaction- or diffusion-limited. Additionally the digestion rate is found to be proportional to the volume around each bond that is accessible to the enzyme, which is determined by the range and radius of the enzyme. Simulations of uniformly mixed susceptible and resistant polymers reveal no significant effect on the digestion of the susceptible polymers due to the presence of the resistant polymers.

Abstract:

We use several techniques to probe the wave functions proposed to describe the A phases by Das, Das, and Mandal [Phys. Rev. Lett. 131, 056202 (2023); Phys. Rev. Lett. 132, 106501 (2024); Phys. Rev. B 110, L121303 (2024).]. As opposed to representing fractional quantum Hall liquids, we find these wave functions to describe states that clearly display strong phase separation. In the process of exploring these wave functions, we have also constructed several new methods for diagnosing phase separation and generating such wave functions numerically. Finally, we uncover a new property of entanglement spectra that can be used as a check for the accuracy of numerics.

Abstract:

A striking series of experiments have observed superconductivity in Bernal-stacked bilayer graphene (BBG) when the energy bands are flattened by applying an electrical displacement field. Intriguingly, superconductivity manifests only at nonzero magnetic fields, or when spin-orbit coupling is induced in BBG by coupling to a substrate. We present detailed functional renormalization group and random-phase approximation calculations that provide a unified explanation for the superconducting mechanism in both cases. Both calculations yield a purely electronic 𝑝-wave instability of the Kohn-Luttinger type. The latter can be enhanced either by magnetic fields or Ising spin-orbit coupling, naturally explaining the behavior seen in experiments.

Abstract: